Many women are divided by cranberry juice or capsules to treat and prevent urinary tract infections, but new Dutch research suggests that antibiotics may be more effective even if they contribute to an increased risk of resistance to antibiotics.
“Berries are less effective in prevention, but they do not produce resistant microorganisms,” said Dr. Susan Gerling, an expert in infectious diseases at the Academic Medical Center in Amsterdam. “Women who have recurrent urinary tract infections do not like to take antibiotics for a long time because they know the problem of resistance.” I think that doctors should discuss the results of this study with individual patients to make the best decision. ”
About half of all women will experience urinary tract infections at some point in their lives, and 30 percent of women will have recurrent infections. Escherichia coli is one of the most common causes of urinary tract infection.
In the study, 221 women were selected with at least three concurrent infections in the year preceding the 12-month course of the antibiotic metoprim-sulfamethoxazole (TMP-SMX) (pacterm, betheparim, cotrim, ceptra), taken once a day with two Placebo pills or a cranberry capsule with 500 milligrams of cranberry extract taken twice a day with a pill.
The women who ate blueberry capsules were at least one ITU more than their counterparts who received the antibiotic, 4 versus 1.8, respectively. Women in the cranberry group developed a new infection four months later, while the infection was repeated within eight months among people who received the antibiotic.
Rates of antibiotic resistance tripled among women in the antibiotic group, but this goes back to the baseline three months after they stopped talking about the drug.
One month later, resistance to antibiotics against E. coli was greater than 85% in the group of antibiotics and less than 30% in women who consumed blueberry extract.
“Cranberry has long been described as a natural preventative of urinary tract infection, and many clinical studies using juice or dry extracts have given credence to this hypothesis,” wrote Bill G. Jurley of the University of Arkansas in Medical Sciences in Little Rock. Editorial article
It is not completely known how UTI cranberry is prevented or completely cured, but cranberry contains fructose (fructose) and proanthocyanidins, which can prevent E. coli from attaching to the bladder walls. The blueberry extract may not be bioavailable, like an antibiotic, which can spoil the results of the antibiotic in this study, Gorelli wrote.
“We use cranberry juice and capsules for a long time,” said Dr. Carolyn Dean, MD, Maui, Hawaii. “It stops bacterial adhesion to the bladder wall.”
Antibiotics kill bacteria, while cranberry extract provides more than a mechanical solution, he said.
Dean said there is still a role for juice and / or cranberry extract in preventing urinary tract infection. “Sexually active women who feel the gap after having sex should take blueberry capsules after intercourse as a preventive measure,” he said. “If you develop a urinary tract infection, you can increase the amount of cranberry extract you take or take antibiotics into account.”